CJC-1295 No DAC + Ipamorelin Blend | Research Grade | COA Verified

Description

Research area: Growth hormone axis and secretagogue research

Product Description

This blend combines two growth-hormone-secretagogue peptides that act on different receptors. CJC-1295 without DAC, also known as Modified GRF(1-29), is a 29-amino-acid analog of growth-hormone-releasing hormone (GHRH) carrying stabilizing substitutions but lacking the Drug Affinity Complex, giving it a short, pulsatile action. Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that mimics ghrelin. The two are paired in research because a GHRH analog and a ghrelin-receptor agonist stimulate growth-hormone release through complementary, non-overlapping mechanisms, a classic model for studying synergistic secretagogue signaling in cell and animal systems.

Mechanism & Research Context

In preclinical models, CJC-1295 No DAC binds the GHRH receptor on pituitary somatotrophs to stimulate synthesis and pulsatile release of growth hormone. Ipamorelin selectively activates the growth-hormone secretagogue receptor (GHSR-1a, the ghrelin receptor), amplifying GH release with high selectivity and minimal effect on cortisol or prolactin. Used together, they allow researchers to study how convergent GHRH and ghrelin-receptor pathways interact to potentiate somatotroph output.

Research Applications

• GHRH receptor signaling on pituitary somatotrophs
• Ghrelin/GHSR-1a receptor selectivity studies (Ipamorelin)
• Synergistic GH-secretagogue pathway research
• Pulsatile growth-hormone release modeling
• Selectivity studies of cortisol/prolactin-sparing secretagogues

Storage & Handling

• Store sealed vials in a cool, dark place for short-term storage and frozen for long-term storage.
• After reconstitution, refrigerate and protect from light and heat.
• Avoid repeated freeze-thaw cycles; handle using standard laboratory safety and aseptic technique.

Product Specifications

• Compound class: Peptide blend: GHRH analog + ghrelin-receptor pentapeptide
• Form: Lyophilized powder
• Purity: ≥ 99% (HPLC verified)
• Appearance: White to off-white powder
• Third-party tested: Yes — Certificate of Analysis (COA) on this product page

Quality & Third-Party Testing

Every batch of CJC-1295 No DAC + Ipamorelin Blend is independently third-party tested in the USA for identity and purity, with a Certificate of Analysis (COA) available on this product page.

Compliance Notice

CJC-1295 No DAC + Ipamorelin Blend is for research use only. It is not intended for human or veterinary use and has not been evaluated by the FDA. By purchasing, the buyer represents and warrants that it will be used solely for in-vitro laboratory research.