Klow Blend (KPV/BPC157/TB4/GHK-CU) | Research Grade | COA Verified

Description

Research area: Anti-inflammatory and tissue-repair multi-peptide research

Product Description

KLOW Blend is a four-component research preparation. KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-MSH, studied as an anti-inflammatory fragment that lacks pigmentary activity. BPC-157 is a gastric-derived 15-amino-acid pentadecapeptide. TB-500 is a synthetic 17-amino-acid fragment of thymosin beta-4 covering the actin-binding domain. GHK-Cu is the copper-bound tripeptide. Relative to the GLOW blend, KLOW adds KPV, layering a melanocortin-derived anti-inflammatory tripeptide onto peptides studied for angiogenesis, cytoskeletal remodeling, and extracellular-matrix turnover, positioning it as a tool for combined inflammation-and-repair research models.

Mechanism & Research Context

Each component is studied at a distinct target. KPV modulates NF-kappaB and MAP-kinase signaling to reduce pro-inflammatory cytokine output in epithelial models, notably without binding melanocortin receptors or raising cAMP. BPC-157 is examined for angiogenesis (Egr-1/NAB2), nitric-oxide, and anti-inflammatory pathways. TB-500 sequesters G-actin via its LKKTET motif to drive cytoskeletal remodeling. GHK-Cu modulates collagen, glycosaminoglycan, and MMP/TIMP dynamics. Research probes how anti-inflammatory and multi-pathway repair signaling combine.

Research Applications

• Studying KPV-driven NF-kappaB and MAP-kinase modulation in epithelial models
• Investigating combined anti-inflammatory and angiogenic (BPC-157) signaling
• Cytoskeletal remodeling and cell-migration assays via TB-500
• Assessing GHK-Cu extracellular-matrix contributions within the blend
• Modeling inflammation-plus-repair dynamics in intestinal and wound systems

Storage & Handling

• Store sealed vials in a cool, dark place for short-term storage and frozen for long-term storage.
• After reconstitution, refrigerate and protect from light and heat.
• Avoid repeated freeze-thaw cycles; handle using standard laboratory safety and aseptic technique.

Product Specifications

• Compound class: Four-component research peptide blend
• Form: Lyophilized powder
• Purity: ≥ 99% (HPLC verified)
• Appearance: White to off-white powder
• Third-party tested: Yes — Certificate of Analysis (COA) on this product page

Quality & Third-Party Testing

Every batch of Klow Blend (KPV/BPC157/TB4/GHK-CU) is independently third-party tested in the USA for identity and purity, with a Certificate of Analysis (COA) available on this product page.

Compliance Notice

Klow Blend (KPV/BPC157/TB4/GHK-CU) is for research use only. It is not intended for human or veterinary use and has not been evaluated by the FDA. By purchasing, the buyer represents and warrants that it will be used solely for in-vitro laboratory research.