PE-22-28

Description

PE-22-28 is a synthetic peptide derived from the naturally occurring neuropeptide spadin, engineered to interact with a key neural target known as TREK-1 (a two-pore domain potassium channel). TREK-1 plays an important regulatory role in neuronal excitability and is highly expressed in regions of the brain associated with mood regulation, memory formation, and learning. Because of this strategic target profile, PE-22-28 has emerged as a highly intriguing compound in advanced neuroscience research.

By binding to and modulating TREK-1 activity, PE-22-28 offers researchers a valuable tool for exploring how this ion channel influences emotional state, cognitive performance, and neural resilience. TREK-1 has long been recognized as a promising target in the study of depression, and spadin-based peptides have generated excitement for their potential to influence mood-related pathways in novel and more biologically precise ways.

Beyond mood research, PE-22-28 is also being investigated for its potential impact on learning and memory processes. Its activity within brain regions tied to neuroplasticity makes it a compelling candidate for studies related to cognitive enhancement and neural adaptability. Researchers are further evaluating its relevance in models of neurological injury, including stroke recovery, where modulation of neuronal signaling can play a significant role in functional restoration.

In addition, PE-22-28 is attracting interest in the field of neurodegenerative research. Scientists are studying how TREK-1 modulation may influence disease processes associated with aging and cognitive decline, including Alzheimer’s and other degenerative conditions. While research is ongoing, this line of investigation highlights the growing recognition of TREK-1 as an important gateway in neurological health science.

With its targeted mechanism and growing scientific attention, PE-22-28 represents an exciting frontier in peptide-based neuroscience research. As our understanding of neural ion channels and brain signaling continues to grow, peptides like PE-22-28 offer a glimpse into the future of precision neurobiology and therapeutic discovery.

Comes in 10mg vial

Provided as lyophilized powder intended strictly for experimental and research applications.