Description
Research area: Combined tissue repair and cytoskeletal research
Product Description
This is a two-component research blend pairing BPC-157, a stable 15-amino-acid gastric-juice-derived pentadecapeptide, with TB-500, the synthetic acetylated actin-binding fragment (the LKKTET region, approximately residues 17-23) of the naturally occurring 43-amino-acid protein thymosin beta-4. Although marketed as thymosin beta-4, TB-500 is specifically this active fragment rather than the full-length protein. The two are combined in research because they act through complementary pathways: BPC-157 emphasizes angiogenic and cytoprotective growth-factor signaling, while TB-500 emphasizes actin regulation and cell migration, giving researchers a combined model of convergent tissue-repair mechanisms.
Mechanism & Research Context
In preclinical models the two components converge on tissue repair through distinct routes. BPC-157 upregulates VEGF-mediated angiogenesis and modulates nitric oxide signaling and endothelial proliferation. TB-500, via its actin-binding motif, promotes G-actin sequestration and cytoskeletal remodeling that support cell migration, alongside anti-inflammatory modulation and endothelial motility. Together they are studied for their convergent angiogenic and cytoskeletal contributions to wound and soft-tissue healing.
Research Applications
- Convergent angiogenic and cytoskeletal repair studies
- Actin regulation and cell-migration assays (TB-500 component)
- VEGF and nitric-oxide angiogenesis research (BPC-157 component)
- Soft-tissue and wound-healing models
- Comparative single-peptide versus blend mechanism studies
Storage & Handling
- Store sealed vials in a cool, dark place for short-term storage and frozen for long-term storage.
- After reconstitution, refrigerate and protect from light and heat.
- Avoid repeated freeze-thaw cycles; handle using standard laboratory safety and aseptic technique.
Product Specifications
- Compound class: Peptide blend: pentadecapeptide + thymosin beta-4 fragment
- Form: Lyophilized powder
- Purity: ≥ 99% (HPLC verified)
- Appearance: White to off-white powder
- Third-party tested: Yes — Certificate of Analysis (COA) on this product page
Quality & Third-Party Testing
Every batch of BPC-157 & TB4(TB500) Blend is independently third-party tested in the USA for identity and purity, with a Certificate of Analysis (COA) available on this product page.
Compliance Notice
BPC-157 & TB4(TB500) Blend is for research use only. It is not intended for human or veterinary use and has not been evaluated by the FDA. By purchasing, the buyer represents and warrants that it will be used solely for in-vitro laboratory research.


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