GHK-CU Raws

Description

Research area: Bulk copper-tripeptide formulation and assay development

Product Description

This is GHK-Cu supplied as a bulk 10-gram raw powder of the copper-bound tripeptide glycyl-L-histidyl-L-lysine complexed with copper(II). Chemically identical to the tripeptide first isolated from human plasma, the copper coordinates at the histidine imidazole and terminal amine to form the characteristic blue complex. As a raw-material presentation, it is oriented toward analytical characterization, stability testing, and preparation of defined stock solutions rather than single-experiment reconstitution. It remains distinct from growth-hormone peptides: its defining chemistry is copper chelation by a three-residue sequence, not somatotropic receptor activity.

Mechanism & Research Context

Research on the GHK-Cu complex centers on copper coordination chemistry and its downstream effects in cell models, where at nanomolar concentrations it modulates collagen and glycosaminoglycan synthesis and degradation and shifts the balance of matrix metalloproteinases and their TIMP inhibitors. In bulk-material workflows the mechanism-relevant parameters studied include copper-binding stoichiometry, complex stability, and purity, which underpin reproducible extracellular-matrix and antioxidant-pathway experiments.

Research Applications

• Preparing defined GHK-Cu stock solutions for extracellular-matrix assays
• Analytical purity and identity verification (HPLC, mass spectrometry)
• Copper-binding stoichiometry and complex-stability characterization
• Formulation and buffer-compatibility studies for downstream cell work
• Reference-material use in fibroblast and keratinocyte remodeling research

Storage & Handling

• Store sealed vials in a cool, dark place for short-term storage and frozen for long-term storage.
• After reconstitution, refrigerate and protect from light and heat.
• Avoid repeated freeze-thaw cycles; handle using standard laboratory safety and aseptic technique.

Product Specifications

• Compound class: Copper-binding tripeptide complex (bulk raw powder)
• Form: Raw powder
• Purity: ≥ 99% (HPLC verified)
• Appearance: Blue to blue-green powder (copper complex)
• Third-party tested: Yes — Certificate of Analysis (COA) on this product page

Quality & Third-Party Testing

Every batch of GHK-CU Raws is independently third-party tested in the USA for identity and purity, with a Certificate of Analysis (COA) available on this product page.

Compliance Notice

GHK-CU Raws is for research use only. It is not intended for human or veterinary use and has not been evaluated by the FDA. By purchasing, the buyer represents and warrants that it will be used solely for in-vitro laboratory research.